Picture of Markus Brinkmann

Markus Brinkmann PhD Associate Professor, School of Environment and Sustainability

Centennial Enhancement Chair in Mechanistic Environmental Toxicology
Director, Toxicology Centre
Faculty Member, Global Water Futures (GWF) program
Member, Global Institute for Water Security (GIWS)

Room 209, 44 Campus Drive

Research Area(s)

  • Exposure and risk assessment modelling
  • Toxicokinetic modelling
  • Aquatic ecotoxicology
  • Mechanistic toxicology
  • Environmental chemistry

Academic Credentials

  • Ph.D. (Biology), RWTH Aachen University, Germany
  • M.Sc. (Ecotoxicology), RWTH Aachen University, Germany
  • B.Sc. (Biology), RWTH Aachen University, Germany

Selected Publications

Freese, M., Rizzo, L., Pohlmann, J.-D., Marohn, L., Witten, PE, Gremse, F. Rütten, S., Güvener, N., Michael, S., Wysujack, K. , Lammers, T., Kiessling, F., Hollert, H., Hanel, R., Brinkmann, M. (2019) Bone resorption and body reorganization during maturation induce maternal transfer of toxic metals in anguillid eels. Proceedings of the National Academy of Sciences of America (PNAS) 116: 11339-11344.

Brinkmann, M., Barz, B., Carrière, D., Velki, M., Smith, K., Meyer-Alert, H., Müller, Y., Thalmann, B., Bluhm, K., Schiwy, S. (2019) Bioactivation of quinolines in a recombinant estrogen receptor transactivation assay is catalyzed by N-methyltransferases. Chemical Research in Toxicology 32: 698-707.

Brinkmann, M., Schlechtriem, C., Reininghaus, M., Eichbaum, K., Buchinger, S., Reifferscheid, G., Hollert, H., Preuss, T.G. (2016) Cross-species extrapolation of uptake and disposition of neutral organic chemicals in fish using a multispecies physiologically-based toxicokinetic model framework. Environmental Science and Technology 50:1914–1923.

Brinkmann, M. & Koglin, S., Eisner, B., Wiseman, S., Hecker, M., Eichbaum, K., Thalmann, B., Buchinger, S., Reifferscheid, G., Hollert, H. ( 2016) Characterization of transcriptional responses to dioxins and dioxin-like contaminants in roach ( Rutilus rutilus ) using whole transcriptome analysis. Science of the Total Environment 541: 412-423.

Schiwy, A. & Brinkmann, M. , Thiem, I., Guder, G., Winkens, K., Eichbaum, K., Nüßer, L., Thalmann, B., Buchinger, S., Reifferscheid, G., Seiler, T.-B., Thoms, B., Hollert, H. (2015) Determination of the dioxin-like potential of single substances, complex mixtures and environmental samples in the Micro-EROD assay with H4IIE cells. Nature Protocols 10, 1728–1741.